If a permanent that would be dealt damage has more than one shield counter on it, that damage is prevented and only one shield counter is removed.

Only the first and second modes of Titan of Industry's triggered ability have a target. If one of those modes is chosen with either the third or fourth mode and the only target is an illegal target when the ability would resolve, the ability does not resolve and the other chosen mode has no effect.

Shield counters don't prevent players from sacrificing creatures.

“Shield” is not an ability that creatures have and shield counters are not keyword counters. If a creature with a shield counter loses its abilities, the shield counter will still protect it as normal.

If a permanent with a shield counter is dealt unpreventable damage, that damage will be dealt and a shield counter will still be removed.

A creature with a shield counter on it may still be destroyed by state-based actions if it has damage marked on it equal to its toughness or has been dealt unpreventable damage by a source with deathtouch.

Removing a shield counter in this way isn't the same as regenerating a creature.