Fugitive Droid's activated ability can target a spell that has multiple targets, as long as at least one of those targets is an artifact or creature you control.

If the artifact or creature you control targeted by the target spell leaves the battlefield, that spell is no longer a legal target for Fugitive Droid's activated ability. On the other hand, if that targeted artifact or creature becomes an illegal target for the target spell but remains on the battlefield under your control, the target spell is still a legal target for Fugitive Droid's activated ability.